Remarkably, the case fatality rate was similar if not higher than in the studies from Europe. Several studies have shown a lower incidence in Asian than in European populations, with recent data from national health insurance claim data in Taiwan showing an incidence of 16.5 per 100 000 per year, i.e., a ten-fold lower incidence than reported from Europe and the USA. This is in part due to the relation between cancer and thrombosis, but even when patients with malignancies are excluded, over 10 % of patients die within the year. Venous thrombosis is a severe disorder with a poor prognosis, with an early case fatality rate of six percent, while 20 % of patients die within a year. 1 shows, the incidence is higher in women up till age 60, and then becomes slightly higher in men than in women. per year, with a slightly higher rate in women (1.6/1000 persons-years (py)) than in men (1.3/1000py). The Tromsø study, in which the whole population of this Nordic city was followed over time, reported an overall incidence of first venous thrombosis of 1. There is a steep age-gradient, which follows a rule of 10: the annual incidence is 1: 100 000 in children, 1:10 000 in reproductive age, 1:1000 in later middle age and 1:100 in the very old. General epidemiology Venous thrombosis by age and sexĭeep vein thrombosis and pulmonary embolism occur in 1– individuals per year. This will lead to risk stratification and targetted prevention and treatment. To reduce the burden of thrombosis, it is necessary to know the factors that contribute to its occurrence. Public awareness of thrombosis is low, and fewer people have basic knowledge of its symptoms and risk factors than they have of other major vascular diseases as myocardial infarction and stroke. It also showed that venous thrombosis was the leading cause of loss of ‘disability-adjusted life years’ (DALYs) in low and medium income countries, and the second leading cause in high income countries, with premature death as the main contributor. It provided data showing that annually over half a million deaths in Euorpe, and over 300 000 in the USA, can be attributed to venous thrombosis. A recent study emphasised the lack of data for many regions of the world. The World Health Organization lists the global impact of a large number of diseases in its Global Burden of Diseases, Injuries and Risk factors (GBD) publications, but does not include venous thrombosis. Venous thrombosis, manifesting mainly as deep vein thrombosis of the lower extremities and pulmonary embolism, is still underresearched and underestimated.
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